Session I, Part I

Moderator:
Jacqui Hecht, University of Texas, Houston

The Nosology of Rare Bone Diseases based upon their clinical, radiographic, histologic, biochemical and molecular characteristics
- Deborah Krakow, University of California, Los Angeles

Osteoblast and osteocyte biology - Lynda Bonewald, University of Missouri, Kansas City

Osteoclast biology - Stuart Ralston, University of Edinburg, United Kingdom

Session I, Part II

Moderator:
Henry Kronenberg, Massachusetts General Hospital, Boston

Chondrocyte biology - Maurizio Pacifici, Children’s Hospital of Pennsylvania

Vascular biology - Bjorn Olsen, Harvard University

Matrix Biology - Brendan Lee, Baylor College of Medicine

Lunch/Keynote Lecture

Coupling knock in mice with massively parallel sequencing to unravel the role of Runx2 in transcriptional regulation of bone cell
differentiation and function - Andy McMahon
University of Southern California

Session II, Part I

Moderator:
Christopher Niyibizi, Pennsylvania State University, Harrisburg

Treating osteoclast over-activity with bisphosphonates and interferon - Graham Russell, University of Oxford

Treating Hypophosphatasia by targeting enzyme replacement therapy to bone - Michael Whyte, Shriners Hospital, St. Louis

Treating skeletal fragility by antibody based inhibition of Wnt or TGFb antagonists - Matthew Warman, Boston Children’s
Hospital

Session II, Part II

Moderator:
Laura Tosi, Children’s National Medical Center

Small molecule inhibitors of the mTor signaling pathway - Denise Adams, Cincinnati Children’s Hospital

Promotion of skeletal anabolism using synthetic polypeptides - Laurence Legeai-Mallet, INSERM, Paris
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Mechanistic and Therapeutic Insights into Skeletal Biology
Learned from the Study of Rare Bone Diseases
Thursday, September 11th, 2014 (One day prior to the ASBMR 2014 Annual Meeting)

To have your abstract considered for a poster presentation at the National Bone Health Alliance/Rare Bone Disease
Patient Network Workshop: Mechanistic and Therapeutic Insights into Skeletal Biology Learned from the Study of
Rare Bone Diseases, in addition to the ASBMR 2014 Annual Meeting presentations, select the box indicating your
willingness in the “Scientific Information” section of the  
ASBMR Abstract Center. The Abstract Submission Deadline
for the ASBMR 2014 Annual Meeting is Wednesday, April 9, 2014, 5:00 p.m., Eastern Daylight Time (EDT). In addition
Up to 20 Young Investigator Travel Grants of $500 each will be given to individuals who are selected to present their
abstract.












































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