Role of Heparan Sulfate
in the Development of the
Central Nervous System
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includes, the EXT genes affects on the brain, neurological, and
muscular symptoms, including scarring.
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Wings of HOPE as we REACH of the
Cure to Multiple Hereditary Exostoses
Press Release 04 / 09 / 07 4:00 pm Eastern time
Abnormal Scarring With Keloid Formation After Osteochondroma Excision in Children With
Multiple Hereditary Exostoses.

Journal of Pediatric Orthopaedics. 27(3):333-337, April/May 2007.

To read the abstract from this research paper

Harish Hosalkar, MD, MBMS (Ortho), FCPS (Ortho), DNB (Ortho); Jared Greenberg, MD;
Rebecca L. Gaugler, BS; Sumeet Garg, MD;
John P. Dormans, MD

Discussion: Abnormal scarring with keloid formation after osteochondroma excision in MHE has not
been previously reported. Although this study has limited numbers, the results demonstrate a
statistically significant correlation between keloid formation and MHE. The risk for abnormal scarring
and keloid formation should be discussed with all patients before surgery.

The MHE Research Foundation greatly appreciates Dr. Dormans, who serves on the Scientific and
Medical Advisory Board of MHERF and all colleagues who conducted this research, as many people
living with MHE / MO / HME have been experiencing this problem of keloid formation after
osteochondroma excision. Our hope  that this research will help educate both the medical and MHE /
MO / HME communities, all should be award that this issue of abnormal scarring is taking place.  
Non Bone Phenotypes

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